目的调查孕产妇血清叶酸的水平,并探讨影响因素。方法随机抽取门诊就诊的孕产妇进行统一血清叶酸检测及问卷调查。结果3 491名调查对象的血清叶酸平均水平为(11.11±8.71)ng/ml;影响因素有文化程度、孕期、妊娠(包含孕前3个月)是否服用叶酸、食用肝脏的频率(P<0.05);影响程度大小为:服用叶酸情况>孕期>文化程度>食用肝脏频率。结论孕产妇血清叶酸水平随着孕期的发展而持续降低。应口服叶酸制剂,提高肝脏的食用频率,以文化程度较低的孕产妇为宣教重点,提高孕产妇叶酸水平,促进母婴的正常发育。 Objective To investigate the serum levels of folic acid in pregnant women and explore the influencing factors. Methods The pregnant women who were randomly selected for outpatient treatment were tested for serum folate and questionnaires. Results The average level of serum folate in 3 491 subjects was (11.11 ± 8.71) ng / ml. The influential factors were education level, the frequency of taking folate and eating liver during pregnancy and pregnancy (including 3 months before pregnancy) (P <0.05) ; The degree of influence is: take folic acid situation> pregnancy> education level> edible liver frequency. Conclusion The level of serum folate in pregnant women continues to decrease with the development of pregnancy. Should be oral folic acid preparations to improve the frequency of eating the liver to lower educational level as the focus of missionary education to improve folic acid levels in maternal and maternal and child to promote normal development.