重金属或放射性元素进入体内,采用螯合剂促排是治本的治疗措施,但却伴有不可避免地把体内某些必需的微量元素(如锌、锰、铜)螯合并带出体外,引起它们不同程度的丢失,随之而带来不同程度的毒副作用.这正是临床螯合治疗中存在的既实际又迫切需要解决的问题.Ca-DTPA是用得最广泛,疗效较满意的螯合剂,因此选用它作为此类药物的代表来进 Heavy metals or radioactive elements into the body, the use of chelating agents to promote discharge is a cure, but accompanied by inevitable some of the body’s trace elements (such as zinc, manganese, copper) chelated and brought out of the body, causing them different The degree of loss, followed by varying degrees of toxic side effects.This is the existence of both clinical chelation therapy is an urgent need to be solved.Ca-DTPA is the most widely used, more satisfactory chelating agent, So choose it as a representative of such drugs come