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为探讨射频消融治疗心房颤动（简称房颤）的可行性，对１０条犬进行单心房Ｂｕｒｓｔ刺激和药物＋心房电刺激建立房颤模型并进行心房外膜多条径线的消融。结果显示：消融径线为连续和透壁性损伤；消融后药物＋心房电刺激的房颤诱发率和平均持续时间与消融前比较差异有高度显著性（５８％ｖｓ１００％，４．５ｓｖｓ２０３．５ｓ，Ｐ均＜０．０１）；校正窦房结恢复时间和窦性心率分别较消融前明显延长６５％（１２９±５１ｍｓｖｓ７８±３４ｍｓ）和下降１２％（１５０±６３ｂｐｍｖｓ１７０±３５ｂｐｍ），而房室传导功能和心脏功能无显著性变化。提示射频消融治疗房颤是可行的，其主要机制为消融径线有效地分离阻隔了参与房颤折返环的心房肌群。１条犬消融后发生持续性窦性停搏，可能是损伤窦房结动脉所致
To explore the feasibility of radiofrequency catheter ablation in the treatment of atrial fibrillation (AF), atrial fibrillation models were established in 10 dogs with single atrium Burst stimulation and drug + atrial electrical stimulation and ablation of atrial endocardial multiliner. The results showed that the ablation line was continuous and transmural damage. The ablation rate and mean duration of atrial fibrillation induced by drug + atrial electrical stimulation after ablation were significantly higher than those before ablation (58% vs100%, 4.5s vs203.5s , P <0.01). The time to correct sinus node recovery and sinus heart rate were significantly longer by 65% (129 ± 51 ms vs 78 ± 34 ms) and 12% (150 ± 63 bpm vs 170 ± 35 bpm) than before ablation, respectively, while atrioventricular conduction No significant changes in function and cardiac function. Prompt radiofrequency ablation of atrial fibrillation is feasible, the main mechanism for the effective separation of the ablation line obstructs the atrial fibrillation involved in atrial fibrillation reentry ring. A dog after ablation sinus continuous beating may be caused by damage to the sinus node arteries