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目的探讨产科妊娠肝内胆汁淤积症ICP的肝功能指标,分析围生儿结局。方法 98例妊娠肝内胆汁淤积症患者做回顾性分析。98例患者为观察组,另选50例健康孕妇为对照组,对两组的围生儿结局做分析。结果观察组患者血清转氨酶、胆汁酸的水平上升,与对照组相比差异有统计学意义(P<0.05)。观察组患者新生儿窒息、早产、围生儿死亡率明显高于对照组,差异有统计学意义(P<0.05)。结论 ICP孕妇预后较好,但围生儿危险增加,需予以高度重视,必要时刻采取剖宫产手术,改善围生儿预后。
Objective To investigate the liver function index of obstetric pregnancy intrahepatic cholestasis ICP and analyze the perinatal outcome. Methods 98 patients with intrahepatic cholestasis of pregnancy were retrospectively analyzed. 98 patients were observed group, another 50 healthy pregnant women as the control group, analysis of the perinatal outcome of the two groups. Results The levels of serum aminotransferase and bile acid in the observation group were significantly higher than those in the control group (P <0.05). The neonatal asphyxia, premature labor and perinatal mortality in the observation group were significantly higher than those in the control group, the difference was statistically significant (P <0.05). Conclusion The prognosis of ICP pregnant women is better, but the perinatal risk increases, which needs to be given high priority. Cesarean section surgery is necessary to improve the prognosis of perinatal children.