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目的 探讨儿童骨髓增生异常综合征的诊断和治疗方法。方法 回顾分析近 1 6年来我院收治的 76例儿童骨髓增生异常综合征的临床表现、骨髓形态学和其它辅助检查及诊治经过 ,对比不同时期的诊断方法及治疗方案。结果 单纯按 FAB的骨髓形态学标准及旧的诊断手段并不完全能满足诊治所需 ,有必要应用更多的辅助方法以减少误诊 ;儿童骨髓增生异常综合征的治疗需要不同的方案。结论 小儿 MDS临床表现不典型 ,诊断本病需慎重 ,有必要应用多种措施 ,治疗方法应个体化。
Objective To investigate the diagnosis and treatment of children with myelodysplastic syndrome. Methods A retrospective analysis of 76 cases of children with myelodysplastic syndrome in our hospital over the past 16 years clinical manifestations, bone marrow morphology and other auxiliary examination and diagnosis and treatment after comparison of different periods of diagnostic methods and treatment options. Results According to the standard of FAB bone marrow morphology alone and the old diagnostic methods are not fully meet the needs of diagnosis and treatment, it is necessary to apply more auxiliary methods to reduce misdiagnosis; children with myelodysplastic syndrome treatment requires different programs. Conclusion The clinical manifestations of pediatric MDS are not typical, the diagnosis of this disease need careful, it is necessary to apply a variety of measures, the treatment should be individualized.