边缘性牙周炎的发病过程与免疫反应密切关联。在免疫反应中T-细胞和B-细胞在牙周炎症感染中,参与了对组织的损伤及应答性反应。以口腔细菌为抗原的B-细胞体液免疫参与了牙周炎的发病,产生了各种免疫球蛋白。而在牙周炎病变中,为了探讨T-细胞的分布及其机能,作者对临床牙周炎患者切除的炎症性龈组织进行了免疫病理学研究。以胸腺作为抗原,免疫家兔,获得抗家兔T-细胞的免疫血清,以通法标记荧光色 The pathogenesis of marginal periodontitis is closely related to the immune response. T-cells and B-cells are involved in tissue damage and responsiveness during periodontal inflammatory infections in an immune response. B-cell humoral immunity, with oral bacteria as an antigen, is involved in the pathogenesis of periodontitis and produces a variety of immunoglobulins. In the periodontal disease, in order to investigate the distribution of T-cells and their function, the authors performed immunopathological studies on inflammatory gingival tissue excised from patients with clinical periodontitis. To thymus as antigen, immune rabbits, rabbit anti-rabbit immune T-cells obtained by the general method fluorescent color