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目的了解2型糖尿病患者糖尿病肾病(DN)患病率及其相关因素。方法对常住本溪市中心城区的2276例2型糖尿病患者进行问卷调查,采集临床资料。结果糖尿病患者DN患病率为20.43%,病程≥10 a者DN患病率(10 a～为25.66%,≥20 a～为39.83%)随病程增长而上升(x~2=17.707,P<0.05)。吸烟(24.46%)、高血压(22.91%)、血脂异常(23.24%)、高尿酸血症(26.83%)、HbA_(1C)≥8%(24.25%)、合并糖尿病周围神经病变(35.22%)者DN患病率高于无相关因素(分别为18.97%,17.58%,12.31%,19.19%,18.50%,13.53%)者(P<0.05)。饮茶者DN患病率低不饮茶者(x~2=5.713,P<0.05)。吸烟(OR=1.817,95%CI:1.372～2.185)、高血压(OR=1.115,95%CI:1.053～1.663)、血脂异常(OR=1.605,95%CI:1.195～2.154)、高尿酸血症(OR=1.544,95%CI:1.269～1.847)、HbA_(1C)≥8%(OR=1.294,95%CI:1.021～1.640)、合并糖尿病周围神经病变(OR=5.797,95%CI:4.580～7.338)是DN患病危险因素。结论有不良生活习惯及糖尿病并发症者DN患病率较高,且是DN患病的危险因素。
Objective To understand the prevalence of diabetic nephropathy (DN) and its related factors in type 2 diabetic patients. Methods A total of 2276 patients with type 2 diabetes mellitus living in downtown Benxi were investigated by questionnaires and clinical data were collected. Results The prevalence of DN was 20.43% in patients with diabetes mellitus, and the prevalence of DN was increased with the duration of disease (10 ~ 25.66%, ≥20 a ~ 39.83%) with the duration of disease (x ~ 2 = 17.707, P < 0.05). Smoking (24.46%), hypertension (22.91%), dyslipidemia (23.24%), hyperuricemia (26.83%) and HbA 1C (24.25%), with diabetic peripheral neuropathy (35.22% The prevalence of DN was higher than those without related factors (18.97%, 17.58%, 12.31%, 19.19%, 18.50%, 13.53% respectively) (P <0.05). The prevalence of DN in tea drinkers was low (x ~ 2 = 5.713, P <0.05). (OR = 1.817, 95% CI: 1.372-2.18), hypertension (OR = 1.115, 95% CI: 1.053-1.663), dyslipidemia (OR = 1.605, 95% CI: 1.195-2.15), high uric acid (OR = 1.544, 95% CI: 1.269-1.847), HbA 1C (≥8%) (OR = 1.294, 95% CI: 1.021-1.640) with diabetic peripheral neuropathy (OR = 5.797, 95% CI: 4.580 ~ 7.338) is a risk factor for DN. Conclusions Adverse lifestyle and diabetic complications have a higher prevalence of DN and are risk factors for DN.