输血已广泛应用于外科实践,然而具有一定的危险,诸如输血反应,代谢紊乱,凝血机能障碍和病毒传播等。近来,输血对免疫系统的影响尤其是对肿瘤手术病人的免疫抑制已引起人们的关注。一、输血对肿瘤手术预后的影响 1982年Burrows等对122例结肠和直肠腺癌术后病人进行调查,发现输血组无复发存活率明显低于未输血组。在术后6～12月 Blood transfusion has been widely used in surgical practice, but there are certain risks, such as transfusion reactions, metabolic disorders, coagulation dysfunction and virus transmission. Recently, the impact of blood transfusion on the immune system, especially the immunosuppression of patients undergoing tumor surgery, has drawn attention. First, the impact of blood transfusion on the prognosis of tumor surgery 1982 Burrows et al. 122 patients with colon and rectal cancer after surgery were investigated and found that blood transfusion group recurrence-free survival was significantly lower than the non-transfusion group. After 6 to 12 months after surgery