综述了无水氯化铈促进多种有机反应及其在有机合成和医药中间体合成中的应用,讨论了向格氏试剂或有机锂中添加无水氯化铈可以有效抑制羰基亲核加成副反应的发生,提高产率和选择性,通过这种方法能合成出各种三级醇,利用有机铈还能与腈反应得到叔甲胺产品。无水氯化铈还可以促进一些其他类型的反应顺利进行。 The application of anhydrous cerium chloride to promote a variety of organic reactions and their applications in organic synthesis and pharmaceutical intermediates is reviewed. The addition of anhydrous cerium chloride to Grignard reagent or organolithium can effectively inhibit carbonyl nucleophilic addition Side reactions, increase productivity and selectivity, through this method can be synthesized a variety of tertiary alcohols, the use of organic cerium can react with the nitrile tert-methylamine products. Anhydrous cerium chloride can also promote the smooth progress of some other types of reactions.