本文对常见的有机溶剂如乙腈、甲醇和乙醇对无机阴离子色谱的保留时间、峰高和半峰宽、峰形和各峰之间的分离度影响进行了研究;发现随着有机溶剂的加入,对离子半径较大,疏水性较强的阴离子,有缩短保留时间的作用;而对离子半径较小,亲水性较强的离子反而增加了保留时间,并对这一现象进行了机理探讨. In this paper, the effects of common organic solvents such as acetonitrile, methanol and ethanol on the retention time, peak height and full width at half maximum, peak shape and resolution between peaks were studied. It was found that with the addition of organic solvents, The ions with larger ionic radius and stronger hydrophobicity have the effect of shortening the retention time. On the contrary, the ions with smaller ionic radius and stronger hydrophilicity increase the retention time, and the mechanisms are discussed.