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本文应用RIA法测定了22例口腔颌面部恶性肿瘤患者的唾液CEA值,并与8例口腔良性疾患及20例健康人作比较.发现:①口腔颌面部恶性肿瘤患者唾液CEA值明显高于口腔良性疾患者(p<0.05)和健康人(p<0.01),异常的阳性率为54.5%.②口腔颌面部恶性肿瘤患者血清CEA值无明显升高,均在正常值范围内.③在口腔恶性肿瘤中,以鳞状细胞癌患者的唾液CEA值增高更为显著(p<0.001),异常的阳性率为70%.
The CEA values of saliva in 22 patients with oral and maxillofacial malignancies were measured by RIA and compared with 8 cases of benign oral diseases and 20 healthy subjects. Findings: 1 CEA values of saliva in patients with oral and maxillofacial malignancy were significantly higher In patients with benign oral diseases (p<0.05) and healthy persons (p<0.01), the abnormal positive rate was 54.5%.2 CEA values of patients with oral and maxillofacial malignancy were not significantly increased, and were all within the normal range. 3 In oral malignancy, the salivary CEA value of patients with squamous cell carcinoma increased more significantly (p<0.001), and the abnormal positive rate was 70%.