培氟沙星为含氟的喹诺酮类抗菌药物,由于本品具有生物利用率高,半衰期长,体内分布广等优点已广泛用于临床,并常与其他药物配伍静脉滴注。临床操作中我们发现,培氟沙星与其他药物配伍时有时出现混浊。文献报道,培氟沙星不能用氯化钠溶液或者含氯离子的溶液稀释。在普外科,胃癌、乳腺癌手术后常联合应用培氟沙星与核糖核酸抗感染及增加机体抵抗力。应用中发现,在两者换瓶时输液管内特别是墨菲氏滴管内立即出现浑浊现象。 Pefloxacin is a fluorine-containing quinolone antibacterial drug. Because of its advantages of high bioavailability, long half-life and wide distribution in vivo, pefloxacin has been widely used in clinical practice and is often used in combination with other drugs for intravenous drip. In clinical practice, we found that pefloxacin appeared turbid sometimes when combined with other drugs. Reported in the literature, pefloxacin can not be diluted with sodium chloride solution or chloride ion solution. In general surgery, gastric cancer, breast cancer surgery often combined application of pefloxacin and ribonucleic acid anti-infective and increase body resistance. Application found that when both bottles change transfusion tube, especially Murphy’s dropper immediately appear turbid phenomenon.