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应用异烟肼的结核病人83例,用伊藤法测定其血浆单胺氧化酶(MAO)。68例(82％)血浆MAO低于正常值(正常人血浆MAO的范围为9～33单位),在7d、14d以内和14d以上,血浆MAO降至9单位以下者分别为9例、10例和49例,15例(18％)血浆MAO未降低,其中5例用药在7d以内、1例服药11d、1例停药14d、8例用药在14d以上。79例(4例未作手术)在麻醉期间慎用了哌替啶、肾上腺素和麻黄碱等,未发生意外。
83 cases of tuberculosis patients with isoniazid, plasma monoamine oxidase (MAO) was measured by Ito method. Sixty-eight patients (82%) had lower plasma MAO (normal plasma MAO ranged from 9 to 33 units). Within 7 days, 14 days and 14 days, plasma MAO decreased to 9 units in 9 and 10 cases, respectively And 49 cases. The MAO of 15 cases (18%) was not reduced. Among them, 5 cases took medicine within 7 days, 1 case took medicine for 11 days, 1 case stopped medicine for 14 days and 8 cases used medicine for more than 14 days. 79 cases (4 cases without surgery) during the anesthesia with caution pethidine, epinephrine and ephedrine, etc., without accidents.