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目的探讨干预前后3种Ⅰ类切口手术围手术期预防抗菌药物的合理使用与干预措施实施的效果。方法抽取干预前、后3种Ⅰ类切口清洁手术出院病历分别为干预前组和干预后组,各120例,进行干预前后预防用抗菌药物合理性进行对照研究。结果干预前组抗菌药物预防使用率为98.33%,干预后组抗菌药物预防使用率为23.33%(P<0.01);抗菌药物预防使用率显著下降,不合理使用抗菌药物现象明显得到改善。结论实施干预措施有效监管效果明显,可显著提高临床抗菌药物的合理使用率,降低医疗费用,为抗菌药物合理使用提供依据。
Objective To investigate the rational use of antimicrobial agents and the effects of interventions during the perioperative period of three kinds of incision operations before and after intervention. Methods Before and after the intervention, the records of three types of incision clean operation were divided into pre-intervention group and post-intervention group, 120 cases in each group. The preventive and rational use of antimicrobial agents was compared before and after the intervention. Results The prevention and treatment rate of antimicrobial agents in the pre-intervention group was 98.33%. The preventive and curative rate of antimicrobial agents in the intervention group was 23.33% (P <0.01). The anti-bacterial and anti-bacterial drug use rate was obviously decreased. Conclusion The effective supervision effect of the intervention is obvious, which can significantly improve the rational use rate of clinical antimicrobial agents, reduce the medical expenses and provide the basis for rational use of antimicrobial agents.