论文部分内容阅读
目的:评价热毒清口服液体外抑制呼吸道合胞病毒(respiratory syncytial virus,RSV)的效果。方法:采用MTT法及细胞病变抑制实验,以病毒唑为阳性对照,测定热毒清口服液在Hep-2细胞中对呼吸道合胞病毒的抑制作用。结果:热毒清口服液的半数中毒浓度(TC50)为9182.4 mg/L,抑制RSV的半数有效浓度(EC50)为559.8 mg/L,治疗指数(TI)为16.4。结论:热毒清口服液在体外实验中对呼吸道合胞病毒有显著抑制作用。
OBJECTIVE: To evaluate the effect of heat-toxic clearing oral liquid on the suppression of respiratory syncytial virus (RSV). METHODS: MTT assay and cytopathic inhibition assays were used. Ribavirin was used as a positive control to determine the inhibitory effect of Reduqing Oral Liquid on respiratory syncytial virus in Hep-2 cells. Results: The half toxic concentration (TC50) of zeaoqing oral liquid was 9182.4 mg/L, the half effective concentration (EC50) of inhibiting RSV was 559.8 mg/L, and the therapeutic index (TI) was 16.4. Conclusion: Hot Tonic Oral Liquid has a significant inhibitory effect on respiratory syncytial virus in vitro.