阿司匹林、对乙酰氨基酚和布洛芬等非处方药物广泛用于缓解各种疼痛。在美国有17%的人群每周至少使用1次阿司匹林,其中28%为45岁的男性,58%的老年人服用阿司匹林以预防心血管疾病,另有23%和17%的人每周至少使用1次对乙酰氨基酚及布洛芬。同时,在美国有3600万人患有听力减退, Over-the-counter medications such as aspirin, acetaminophen and ibuprofen are widely used to relieve various types of pain. In the United States, at least 17% of people use aspirin at least once a week, 28% of them are 45-year-old men and 58% of the elderly take aspirin to prevent cardiovascular disease. Another 23% and 17% use it at least weekly 1 acetaminophen and ibuprofen. Meanwhile, 36 million people in the United States suffer from hearing loss,