论文部分内容阅读
药品不良反应事件层出不穷。药品作为一种特殊商品,效益与风险并存。药品在治疗疾病的同时,也会导致药品不良反应(ADR)的发生。尽管各国为保障药品安全有效,建立了一系列严格的药品准入制度,但受科技发展和人们认知水平的限制,药品不良反应事件难以避免。据统计,美国住院病人的严重ADR发生率为6.7%,致命ADR发生率为0.32%;1994年有221.6万住院患者发生严重不良反应,导致10.6万人死亡,死亡率高于肺病和糖尿病。我国住院人次每年5000多万,发生ADR的达250多万人,其中死于药物不良反应的有近20万人。
Adverse drug reactions after another. Drugs as a special commodity, benefits and risks co-exist. Drugs in the treatment of diseases, but also lead to the occurrence of adverse drug reactions (ADR). Although various countries have established a series of strict drug access systems to ensure drug safety and effectiveness, the adverse drug reaction events are unavoidable due to technological developments and people’s cognitive limitations. Statistics show that the incidence of serious ADR was 6.7% and the incidence of fatal ADR was 0.32%. In 1994, there were 2,261,000 hospitalized patients with serious adverse reactions, resulting in 106,000 deaths, the mortality rate is higher than that of lung disease and diabetes. Inpatients in China each year more than 50 million, ADR occurred more than 2.5 million people, of which nearly 200,000 people died of adverse drug reactions.