囊性纤维变性是由囊性纤维变性透膜调节基因(CFTR)变异引起的遗传性疾病 ,目前尚无特殊治疗方法。由于上颌窦粘膜上皮特性和下呼吸道粘膜上皮相似 ,因而可利用上颌窦作为评价囊性纤维变性新的治疗方法的实验对象。该作者采用相关腺病毒载体(AAV- CFTR) ,将 CFTR c DNA转入上颌 Cystic fibrosis is a genetic disorder caused by the mutation of the cystic fibrosis transmembrane regulatory gene (CFTR). There are currently no specific treatments. As the maxillary sinus mucosal epithelium and lower respiratory tract mucosal epithelium similar to the use of the maxillary sinus can be used as a new cystic fibrosis evaluation of the treatment of experimental subjects. The authors used the associated adenovirus vector (AAV-CFTR) to transform CFTR c DNA into the maxilla