论文部分内容阅读
蛇床子素能较强地抑制小鼠被动皮肤过敏(PCA)反应,对整体豚鼠组胺性喘息具有保护作用,对慢反应物质(SRS-A)引起的豚鼠离体回肠收缩以及豚鼠离体回肠的Schultz-Dzle反应呈明显的拮抗和阻断作用,并能抑制大鼠腹腔肥大细胞脱颗粒。上述作用均呈一定的剂量依赖关系。
Osthole can strongly inhibit the mouse passive cutaneous anaphylaxis (PCA) response, the overall guinea pig histamine wheezing has a protective effect on slow response substances (SRS-A) induced guinea pig ileum contraction in vitro and isolated guinea pig ileum Schultz-Dzle reaction was significantly antagonistic and blocking effect, and can inhibit rat peritoneal mast cells degranulation. The above effects showed a certain dose-dependent relationship.