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作者将1976年到1986年在加里福尼亚牙科医学院口腔科进行诊治的95名多形性红斑(EM)患者进行回顾性研究,旨在评价EM 的临床特征和发生类型及治疗效果.患者包括女57名,男38名,年龄17岁～77岁(平均43岁)。诊断依据典型的临床表现和常规活检。对可疑患者,作免疫荧光测定。对疑有真菌感染的患者进行了白色念珠菌的培养。作者将患者分为三组:单纯口腔病变组,口腔和唇病变组及口腔、唇和皮肤病变组。研究结果表明,43%患者仅有口腔病变;73%患者为非周期性(慢性)发作;患者自限、周期发作期为3天～21天(平均3周)。服药患者仅占30%,停药或变更药物并不改变患者的体征和症状。在48名患者中,29名为白色念珠菌培养阳性(14名仅口腔病变,13名有口腔、唇病变,2
The authors retrospectively reviewed 95 patients with polymorphous erythema (EM) diagnosed at the Department of Stomatology, School of Dentistry, University of California, from 1976 to 1986 to evaluate the clinical features and types of EM and the effect of treatment. Including 57 women, 38 males, aged 17 to 77 years (mean 43 years). Diagnosis based on typical clinical manifestations and routine biopsy. Suspicious patients for immunofluorescence assay. Candida albicans was cultured in patients with suspected fungal infections. The patients were divided into three groups: simple oral disease group, oral and lip lesions group and oral, lip and skin lesions group. The results showed that only 43% of patients had oral lesions; 73% of patients had non-periodic (chronic) episodes; and patients were self-limited with periods of 3 to 21 days (mean, 3 weeks). Only 30% of patients taking medication, withdrawal or change in the drug does not change the patient's signs and symptoms. Of the 48 patients, 29 were Candida albicans-positive (14 only oral lesions, 13 with oral and lip lesions, 2