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活血化瘀中药丹参具有抗血栓形成、抗血小板、抗凝血、促纤溶、扩血管等作用。目前,丹参注射液已广泛应用于临床。据报道,对心肌梗塞、心绞痛、缺血性脑血管病、脉管炎等血栓栓塞性疾病有较满意的疗效。但最近傅氏等报道复方丹参注射液有促进大鼠 Walker 256癌细胞血行播散的作用。复方丹参注射液由丹参及降香各一半组成,其中丹参为主药。为此,我们按照傅氏等报告的方法观察了丹参对大鼠Walker 256癌细胞血行播散的影响。
Blood circulation and blood stasis Salvia miltiorrhiza has anti-thrombotic, anti-platelet, anti-coagulation, fibrinolysis, and vasodilator effects. At present, Danshen injection has been widely used in clinical. According to reports, it has a satisfactory effect on thromboembolic diseases such as myocardial infarction, angina pectoris, ischemic cerebrovascular disease, and vasculitis. However, recently, Fu et al. reported that Salvia miltiorrhiza injection can promote the hematogenous dissemination of Walker 256 cancer cells in rats. Compound Salvia miltiorrhiza injection is composed of half of Salvia miltiorrhiza and Danxiang, among which Danshen is the main drug. To this end, we observed the effects of salvia miltiorrhiza on hematopoietic spread of Walker 256 cancer cells in accordance with the methods reported by Fu et al.