论文部分内容阅读
目的探讨奥美拉唑在临床应用中的不良反应,分析其一般规律及特点。方法采用手工检索《中国生物医学光盘数据库》和《CNKI医药卫生期刊全文数据库》的方法,筛选出奥美拉唑不良反应的病例报道及临床应用研究中不良反应资料,并查阅全文,进行归纳统计和分类。统计分析性别、年龄、用药情况、ADR所累及的器官或系统与临床表现、治疗以及转归情况。结果实验结果中涉及器官或系统在前3位的是过敏反应(30.2%)、胃肠道系统(19.2%)、血液系统(11.4%)、内分泌系统(11.4%)。结论奥美拉唑在临床应用引起的不良反应值得关注,为安全、合理、有效的用药,应严格掌握适应证使用,避免大剂量。
Objective To investigate the adverse reactions of omeprazole in clinical application and to analyze its general rules and characteristics. Methods A manual search of “China Biomedical CD-ROM Database” and “CNKI Journal of Medicine and Health Journal Full-text Database” were conducted to screen out the case reports of adverse reactions of omeprazole and adverse drug reactions data in clinical application. The full text was summarized and summarized. And classification. Statistical analysis of sex, age, medication, ADR involved organs or systems and clinical manifestations, treatment and outcome. Results The first three organs or systems involved in the experiment were allergic reaction (30.2%), gastrointestinal system (19.2%), hematological system (11.4%) and endocrine system (11.4%). Conclusion Omeprazole deserves attention in the clinical application of adverse reactions, for safe, reasonable and effective medication, should be strictly used indications, to avoid high doses.