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针刺的镇痛作用是人所共知的,而针刺止痛是有其物质基础的。近年来神经生理学与内分泌学在研究中发现,体内存在一类具有吗啡作用的多肽物质,统称为内啡素(Endopbins)。这些具有鸦片样活性的多肽物质与体内的鸦片受体有很强的亲和力。实验证明吗啡及其同类止痛刺乃是通过鸦片受体相结合,然后产生镇痛作用。在镇痛过程中,中枢神经系统内有无内啡素类物质释放,是验证内啡素在痛觉调整过程中是否起作用的重要依据。大量的实验室研究证实针刺镇痛或麻醉的过程中,脑脊液或脑组织中内啡素含量显著增加,直接证明内啡素与针刺作用有极为密切关系。目前比较简单的推想是,针刺体表之某些穴位,使刺激局部产生传入冲动,并到达中枢神经的某
The analgesic effect of acupuncture is known to everyone, and acupuncture has its material basis. In recent years, neurophysiological and endocrinological studies have found that there is a class of polypeptide substances that have morphine action in vivo, collectively referred to as endopbins. These opioid-like polypeptides have a strong affinity with opioid receptors in vivo. Experiments have shown that morphine and its equivalent painkillers are combined through opioid receptors and then produce analgesic effects. In the process of analgesia, whether there is release of endorphins in the central nervous system is an important basis to verify whether or not endorphins play a role in the pain adjustment process. A large number of laboratory studies have confirmed the significant increase of endorphins in cerebrospinal fluid or brain tissue during acupuncture analgesia or anesthesia, which directly proves that endorphins are closely related to acupuncture. At present, it is simpler to infer that certain acupuncture points on the body surface of the acupuncture point cause the local impulse to generate impulses and reach a central nervous system.