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自O′Brien 与 Stout 报导以来,恶性纤维组织细胞瘤已成为骨和软组织的重要恶性肿瘤,但发生在其他部位者很少见。本文描述一例经尸解证实的心脏内恶性纤维组织细胞瘤,使用光镜、电镜及免疫组织化学进行研究。本病例是文献上记载的心脏恶性纤维组织细胞瘤的第4例,免疫组化研究包括膜受体分析,发现组织细胞样细胞与纤维母细胞是有区别的。所报导的是一例29岁,女性患者的尸解病例,因心脏的恶性纤维组织细胞瘤而死于心衰和血栓形成。经光镜及电镜下观察有典型的车幅形,多形性组织细胞和纤维母细胞,完全符合由 Fnzinger 和 Enjoji 等所描述的典型恶性纤维组织细胞瘤的诊断标准,把心脏
Since O’Brien and Stout reported that malignant fibrous histiocytoma has become an important malignant tumor of bone and soft tissue, it is rarely seen in other sites. This article describes an example of intracardiac malignant fibrous histiocytoma confirmed by autopsy and studied using light microscopy, electron microscopy, and immunohistochemistry. This case is the fourth case of malignant fibrous histiocytoma of the heart recorded in the literature. Immunohistochemical studies including membrane receptor analysis revealed that there is a difference between histiocyte-like cells and fibroblasts. The report is a case of a 29-year-old woman who died of autopsy and died of heart failure and thrombosis due to malignant fibrous histiocytoma of the heart. Under the light microscope and electron microscope, there are typical vehicle shape, pleomorphic histiocytes and fibroblasts, which fully comply with the diagnostic criteria of typical malignant fibrous histiocytoma described by Fnzinger and Enjoji et al.