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F-30066經实驗証明对动物血吸虫病有显著的疗効,最近临床上亦广泛采用,关于F-30066对血吸虫的作用机制,迄今不明。过去我們曾就F-30066对体外血吸虫糖原含量的影响进行了測定,本文进一步覌察了F-30066对家兎体內血吸虫成虫的核酸、糖原含量的影响。方法血吸虫成虫来源是以江西湖沼地区自然阳性釘螺体
F-30066 has been proved to have significant therapeutic effects on animal schistosomiasis. It has been widely used clinically recently. The mechanism of action of F-30066 against schistosomiasis has so far been unknown. In the past we had on the F-30066 in vitro Schistosoma japonicum glycogen content were measured in this paper further investigated F-30066 on the snail adult snails adults nucleic acid, glycogen content. Methods Schistosoma japonicum was originated from naturally occurring snails in Hunan Lake Marsh area