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目的探讨分析运用养血调经法联合TAC方案(多西他赛+多柔比星+环磷酰胺)化疗治疗乳腺癌术后患者疗效。方法选择99例行TAC方案化疗的乳腺癌术后患者,按治疗方法不同分为2组:治疗组42例采用养血调经法联合TAC方案化疗,对照组57例行TAC方案化疗,治疗4个周期后观察疗效。结果临床症状改善治疗组有效39例,对照组35例,总有效率:治疗组为92.9%,对照组为61.4%。化疗不良反应发生率:治疗组为9.5%,对照组为78.9%。2组有效率及化疗不良反应发生率比较差异有统计学意义(P均<0.05)。结论养血调经法联合化疗治疗乳腺癌可改善临床症状,减轻化疗毒副反应,提高患者生活质量,减少复发率,延长患者生存期。
Objective To investigate the effect of nourishing blood and regulating menstruation combined with TAC regimen (docetaxel + doxorubicin + cyclophosphamide) in the treatment of postoperative patients with breast cancer. Methods Ninety-nine patients with postoperative breast cancer treated with TAC regimen were divided into two groups according to different treatment methods: 42 cases in the treatment group were treated with TAC regimen combined with nourishing blood and regulating menstruation, 57 cases in control group were treated with TAC regimen and 4 cases were treated Observed after the cycle effect. Results Clinical symptoms improved 39 cases in the treatment group and 35 cases in the control group. The total effective rate was 92.9% in the treatment group and 61.4% in the control group. The incidence of adverse reactions of chemotherapy was 9.5% in the treatment group and 78.9% in the control group. There was significant difference between the two groups in the incidence of chemotherapy and ADR (all P <0.05). Conclusion Nourishing blood and regulating menstruation combined with chemotherapy for breast cancer can improve clinical symptoms, reduce chemotherapy side effects, improve patient quality of life, reduce the recurrence rate and prolong the survival of patients.