应用活血化瘀片对大白鼠的实验性肝损伤进行了研究,以死亡率、体重变化、肝/体重和脾/体重比值、~(14)C 氨基比林呼吸试验、肝脏蛋白结合羟脯氨酸和病理检查作为对比指标。实验结果显示:活血化瘀片无毒性作用,可使正常大白鼠肝脏蛋白结合羟脯氨酸减少,在减少病死率和减轻肝硬变的形成上,有一定的保护作用。 Experimental liver damage in rats was studied with Huoxue Huayu Tablets, mortality, weight change, liver/body weight and spleen/body weight ratio, ~(14)C aminopyrine breath test, liver protein binding oxindole Acid and pathological examinations were used as comparison indicators. The experimental results show that: Huoxuehuayu tablets have no toxic effect, which can reduce the protein binding of hydroxyproline in normal rats, and have a certain protective effect in reducing the mortality and reducing the formation of liver cirrhosis.