【摘 要】
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Dear Editor,The Ras superfamily of GTPases are conserved in eukaryotes from yeast to humans,and play essential roles in the regulation of a variety of key cellu
【机 构】
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Key Laboratory of Bioactive Peptides of Yunnan Province/Key Laboratory of Animal Models and Human Di
论文部分内容阅读
Dear Editor,The Ras superfamily of GTPases are conserved in eukaryotes from yeast to humans,and play essential roles in the regulation of a variety of key cellular processes,including cell differentiation and proliferation,membrane trafficking,nuclear import and export,cytoskeletal remodeling and mitogenic signaling (Kamoub and Weinberg,2008).Notably,numerous studies have shown that many members of the Ras-related small GTPases are involved in diverse aspects of tumorigenesis and tumor progression (Chen et al.,2014;Liu et al.,2017).
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