胶态酒石酸铋是一种新型铋制剂,本文报道该药对兔实验性非特异性溃疡性结肠炎的治疗作用。l实验方法按文献略加改进复制兔溃疡性结肠炎模型。取模型制备成功者40只.随机均分为4组;胶态酒石酸铋组、柳氮磺胺吡啶组.胶态次枸橼酸铋组及生理盐水组,各组均按0.5 g·kg~(-1)·d~(-1)ig.用药5 d后将动物处死。从肛门齿状线始作结肠大体标本观察.测定病变范围及程度.并在病变部位取材、固定、切片、HE染色镜检。 Colloidal bismuth tartrate is a novel bismuth preparation reported herein for the treatment of experimental nonspecific ulcerative colitis in rabbits. l experimental method according to the literature slightly improve the model of rabbit ulcerative colitis. Forty successful models were prepared and divided into four groups randomly: the group of colloidal bismuth tartrate, the group of sulfasalazine, the group of colloidal bismuth subcitrate and the group of normal saline, all groups were treated with 0.5 g · kg ~ (-1) -1) · d ~ (-1) ig. The animals were sacrificed after 5 days. Starting from the anterior dentition of colonic colon specimens, the extent and degree of lesions were determined, and the lesions were taken, fixed, sectioned and stained with HE.