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目的分析探讨多巴酚丁胺与巴胺联合治疗小儿重症肺炎的临床效果。方法选取我院2011年8月~2013年8月收治的68例重症肺炎患儿作为研究对象,按照患儿就诊顺序编号将其随机分为两组,对照组患者行常规治疗,研究组患者在常规治疗的基础上行多巴胺联合多巴酚丁胺治疗,观察两组患儿病情改善效果。结果研究组患儿治疗后显效率为52.9%,总有效率为97.1%,对照组显效率为35.3%,总有效率为85.3%,研究组患儿治疗效果明显优于对照组;研究组患儿炎症吸收率达85.3%,对照组患儿炎症吸收率为61.8%,组间比较差异有统计学意义(P<0.05);研究组患者治疗后发热、心率、喘息、肺部啰音等病症改善效果明显优于对照组(P<0.05);两组均无严重不良反应发生。结论对重症肺炎患儿行小剂量多巴胺联合多巴酚丁胺治疗能切实改善患儿病症,具有显著的临床有效性与安全性,可以进行推广应用。
Objective To investigate the clinical effect of dobutamine and dopamine in the treatment of pediatric severe pneumonia. Methods Sixty-eight children with severe pneumonia admitted from August 2011 to August 2013 in our hospital were enrolled in this study. The patients were randomly divided into two groups according to their order numbers. The patients in the control group were treated routinely. On the basis of routine treatment of dopamine and dobutamine treatment, two groups of children to observe the effect of improvement. Results After treatment, the effective rate of children in study group was 52.9%, the total effective rate was 97.1%, the effective rate of control group was 35.3% and the total effective rate was 85.3%. The therapeutic effect of study group was better than that of control group. The infantile inflammatory absorption rate was 85.3% in the control group and 61.8% in the control group, with significant difference between the two groups (P <0.05). The fever, heart rate, wheezing and pulmonary rales in the study group The improvement effect was obviously better than that of the control group (P <0.05). No serious adverse reactions occurred in both groups. Conclusion Small doses of dopamine combined with dobutamine in children with severe pneumonia can effectively improve the condition of children with obvious clinical efficacy and safety and can be popularized and applied.