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目的:观察胰岛素与口服降糖药物治疗对初诊2型糖尿病患者胰岛β细胞功能的影响。方法:将本院初诊2型糖尿病患者分为A组、C组与B组,分别采用不同方法治疗。结果:A组与B组患者,治疗效果对比无统计学差异(p>0.05)。C组患者FPG、HbA1C、FIns与HOMA-β指标改善情况相对较差,与上述两组对比,统计学差异显著(p<0.05)。结论:将胰岛素与口服降糖药物交替用于初诊2型糖尿病患者的治疗,可有效促进患者胰岛β细胞功能增强(恢复),对胰岛功能的影响不劣于胰岛素,临床价值显著。
Objective: To observe the effects of insulin and oral hypoglycemic agents on pancreatic β-cell function in newly diagnosed type 2 diabetic patients. Methods: Patients with newly diagnosed type 2 diabetes in our hospital were divided into group A, group C and group B, and were treated with different methods. Results: There was no significant difference in therapeutic effect between group A and group B (p> 0.05). The improvement of FPG, HbA1C, FIns and HOMA-β in group C was relatively poor, which was significantly different from the above two groups (p <0.05). Conclusion: The insulin and oral hypoglycemic drugs used in the treatment of newly diagnosed type 2 diabetic patients can effectively promote the function of pancreatic β-cell enhancement (recovery), the islet function is not inferior to insulin, the clinical value was significant.