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目的研究血清中C-反应蛋白(CRP)水平与急性脑梗死的关系。方法采用免疫比浊法测定80例脑梗死患者入院第1、7、14、21、28d的血清中CRP水平,并与80例健康人作对照。结果与健康对照组比较,脑梗死血清中CRP浓度差异有统计学意义(P<0.01),在起病第3d脑梗死组CRP浓度为(12.5±4.3)mg/L,又明显高于对照组[(3.5±1.1)mg/L]。结论血清CRP水平增高与脑梗死的发生和严重程度有密切关系。
Objective To study the relationship between serum C-reactive protein (CRP) level and acute cerebral infarction. Methods Serum levels of CRP were measured in 80 patients with cerebral infarction on the 1st, 7th, 14th, 21st and 28th days by immunoturbidimetry and compared with 80 healthy people. Results Compared with the healthy control group, the serum CRP levels in cerebral infarction were significantly different (P <0.01). The CRP concentration in the third cerebral infarction group was (12.5 ± 4.3) mg / L, which was significantly higher than that of the control group [(3.5 ± 1.1) mg / L]. Conclusion The increase of serum CRP is closely related to the occurrence and severity of cerebral infarction.