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视网膜母细胞瘤(Rb)是幼儿眼内最常见的肿瘤。分子生物学研究证实其发生之关键在于Rb基因的纯合型丢失,该基因定位于13号染色体长臂1区4带(13q14),系隐性基因,也是最早发现的抗癌基因。然而在大多数Rb,13q14
Retinoblastoma (Rb) is the most common tumor in young children’s eyes. Molecular biology confirmed that the key to its occurrence is the loss of the homozygous Rb gene. The gene is located on the region of the long arm of chromosome 13 in region 1 and 4 (13q14). It is the recessive gene and the earliest discovered anti-oncogene. However on most Rb, 13q14