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本文研究了慢性萎缩性胃炎（ｎ＝２７）、胃溃疡（ｎ＝２５）、十二指肠溃疡（ｎ＝２１）患者ＨＰ感染和血清胃泌素水平的变化，并以２４例正常人作对照。结果表明，治疗４～６周后ＨＰ阳性率明显降低（Ｐ均＜０．０１），血清胃泌素水平在治疗前，萎缩性胃炎（５８．４６±２１．７４ｎｇ／Ｌ）、胃溃疡（６２．６９±２６．８５ｎｇ／Ｌ）和十二指肠溃疡（６６．３８±２９．９２ｎｇ／Ｌ）均明显高于正常人（３０．１２±１２．０４ｎｇ／Ｌ）（Ｐ＜０．０１），治疗４～６周后胃泌素水平均明显降低（Ｐ＜０．０１），提示ＨＰ感染是萎缩性胃炎、消化性溃疡的致病因素。并可引起胃泌素血症，ＨＰ的消除和疾病的治愈或好转，血清胃泌素水平随之降低或恢复正常
In this paper, the changes of HP infection and serum gastrin levels in patients with chronic atrophic gastritis (n = 27), gastric ulcer (n = 25) and duodenal ulcer (n = 21) Control. The results showed that the positive rate of HP was significantly decreased after 4 to 6 weeks of treatment (all P <0.01), and the level of serum gastrin before treatment was ametropic (58.46 ± 21.74ng / L), gastric ulcer 62.69 ± 26.85ng / L) and duodenal ulcer (66.38 ± 29.92ng / L) were significantly higher than those in normal people (30.12 ± 12.04ng / L) (P <0.01) ), Gastrin levels were significantly decreased after 4 to 6 weeks of treatment (P <0.01), suggesting that HP infection is a causative agent of atrophic gastritis and peptic ulcer. And can cause gastrin, HP elimination and cure or improvement of the disease, serum gastrin levels decreased or returned to normal