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过去对豚鼠包涵体性结膜炎衣原体(GPIC)免疫反应的研究表明,在抵抗和消退生殖道的衣原体感染中体液免疫是必需的。同时亦指出,细胞免疫单独不能使感染消退或提供抗感染免疫力。然而并不排除细胞免疫参与体液免疫反应。因此,作者用兔抗豚鼠胸腺细胞血清(ATS)处理生殖道感染GPIC的雌性豚鼠,以检验细胞免疫的作用。实验采用Hartley系雌性豚鼠,体重400～500克,血清GPIC抗体阴性,单只关养在装有玻璃纤维过滤顶的笼子里。每只豚鼠给予阴道内接种0.05ml卵黄囊培养的
In the past studies of guinea pig’s inclusion of C.conjunctivum Chlamydia (GPIC) have shown that humoral immunity is essential in chlamydial infections that counteract and regress the genital tract. At the same time also pointed out that the cellular immunity alone can not make the infection subsided or provide anti-infective immunity. However, cellular immunity is not excluded from the humoral immune response. Therefore, the authors treated GPIG-infected female guinea pigs with rabbit anti-guinea pig thymocyte serum (ATS) to examine the effects of cellular immunity. The Hartley female guinea pigs weighing 400-500 g were used in the experiment. Serum GPIC antibodies were negative and kept in a cage with a glass fiber filter top only. Each guinea pig was intravaginally inoculated with 0.05 ml yolk sac