肝细胞癌的总体疗效不佳,基础研究与临床实践之间的巨大鸿沟是导致疗效难以进一步提高的瓶颈。转化医学从肝癌的早期诊断、药物筛选、干预新策略的制定、现有治疗方法不足的弥补以及复发转移的早期预测等方面为肝癌实现从基础研究到临床实践的跨越搭建了重要桥梁。 The overall curative effect of hepatocellular carcinoma is not good, and the huge gap between basic research and clinical practice is the bottleneck that makes the curative effect difficult to be further improved. Translational medicine has built an important bridge for the realization of liver cancer from basic research to clinical practice in terms of early diagnosis of liver cancer, screening of drugs, formulation of new intervention strategies, making up for deficiencies in treatment, and early prediction of recurrence and metastasis.