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结合内镜检查,从粘液池抽取清晨、空腹胃液,以其pH、游离酸、蛋白酶、粘液、胆汁酸及 DNA 值绘制直方图,对比胃癌、胃溃疡、十二指肠溃疡及胆汁(碱性)返流性胃炎各自的图型特征,并用微机进行多元直线回归分析。结果显示胃癌组胃液成分呈游离酸、蛋白酶、粘液含量降低,而胆汁酸含量升高,尤其是 DNA 含量居各组之首,与 pH 值之升高程度相齐,从而呈拱门状图型;胆汁返流组的胆汁酸含量最高,与 DNA 柱相平,亦与 pH 值的柱高相平,故呈三个高柱柱高相齐的特征性图型。消化性胃溃疡组的胃液成分图型与正常组基本相似,但胆汁酸与 DNA 柱有明显增高;而十二指肠溃疡组的突出表现为游离酸柱居各种胃病组之冠,蛋白酶和粘液含量亦相应较高。
Combined with endoscopy, morning and fasting gastric juices were drawn from the mucus pool and histograms were drawn with their pH, free acid, protease, mucus, bile acid, and DNA values to compare gastric cancer, gastric ulcer, duodenal ulcer, and bile (alkaline) ) The respective pattern features of reflux gastritis, and the use of computer for multivariate linear regression analysis. The results showed that the content of gastric juice in gastric cancer group was decreased in free acid, protease, and mucus content, while the bile acid content was increased, especially the DNA content ranked first in each group, which was in line with the increase of pH value, thus showing an arch pattern; The bile reflux group had the highest bile acid content, which was flat with the DNA column and also with the pH column height. Therefore, it was a characteristic pattern with three high column heights. The pattern of gastric juice in the peptic ulcer group was basically similar to that of the normal group, but the bile acid and DNA columns were significantly higher; while the duodenal ulcer group had the prominent free acid column in the top of all stomach groups, protease and The mucus content is also relatively high.