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【目的】比较丝线间断缝合加结扎术与可吸收缝线聚羟基乙酸(Dexon)连续缝合加结扎术处理肺癌支气管残端的临床疗效差异。【方法】回顾性分析1998年3月～2008年3月668例肺癌患者在我院行肺癌根治术,86例患者行丝线间断缝合加结扎术处理支气管残端,582例患者可Dexon线连续缝合加结扎术。【结果】围手术期丝线缝合组支气管胸膜瘘的发生率2.33%,干咳的发生率为39.53%,Dexon线缝合组的发生率分别是0.34%、10.48%,两组比较差异均有统计学意义(P值分别为0.026、<0.001);后期丝线缝合组刺激性干咳的发生率为8.14%,Dexon线缝合组为2.06%,差异有统计学意义(P=0.002)。围手术期和后期咯血、肺不张的发生率在两组之间差异均无统计学意义。围手术期阻塞性肺炎的发生率在两组之间亦无显著性差异。【结论】可吸收缝线聚羟基乙酸(Dexon)连续缝合加结扎术处理肺癌支气管残端可明显减少术后刺激性干咳、支气管胸膜漏等并发症的发生。
【Objective】 To compare the clinical curative effect of interrupted suture plus ligation and absorbable suture Dexon continuous suture plus ligation on bronchial stump of lung cancer. 【Methods】 A retrospective analysis of 668 lung cancer patients undergoing radical resection of lung cancer in our hospital from March 1998 to March 2008 was performed. 86 patients underwent interrupted suture and ligation of silk thread to treat bronchial stump. 582 patients were treated with Dexon continuous suture Plus ligation. 【Results】 The incidence of bronchopleural fistula in perioperative silk suture group was 2.33%, the incidence of dry cough was 39.53%, the incidence of Dexon suture group was 0.34% and 10.48%, respectively, with significant difference between the two groups (P = 0.026, <0.001). The incidence of irritating dry cough in the late silk suture group was 8.14% and that in the Dexon suture group was 2.06%, with a significant difference (P = 0.002). Perioperative and late hemoptysis, the incidence of atelectasis in both groups, the difference was not statistically significant. There was no significant difference in the incidence of perioperative obstructive pneumonia between the two groups. 【Conclusion】 Sexible suture Dexon suture and ligation of bronchial stumps in lung cancer can significantly reduce the occurrence of postoperative complications such as irritating cough and bronchial pleural leakage.