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患者女,2岁,因右腹股沟皮肤巨大黑痣入院。患者出生后即被发现右腹股沟皮肤有一片漆黑色区,其面积为6×5cm,累及右大腿上1/3及右下腹壁。黑色区早界限清楚,边缘规则,平坦,无出血及破溃。随年龄增长,黑色区相应增大,少部分区表面粗糙,可见毛发生长,偶有搔痒感。血尿便常规检查均未见异常。病理检查切除皮肤组织一块,16×12×0.3cm,表面为黑色、未见隆起。切面可见黑色区深为0.1cm。另外见红褐色组织一堆,其大小为4×3×1cm,其中找见淋巴结样组织9块,直径0.2cm至0.5cm不等。镜下表皮基底部可见成巢、条索形或弥漫分布的痣细胞团,直皮内可见成巢的痣细胞团。淋巴结可见皮窦内,淋巴滤泡内或滤泡间有成巢或条
The patient, 2 years old, was admitted to the hospital due to a huge hernia in her right groin. After birth, the patient’s right groin skin was found to have a painted black area with an area of 6 x 5 cm, involving the right 1/3 of the upper thigh and the right lower abdominal wall. The black zone has a clear boundary as early as possible. The edges are regular, flat and free from bleeding and ulceration. As the age increases, the black area increases accordingly, and the surface of a few areas is rough, visible hair growth, occasional pruritus. Routine examination of hematuria was not abnormal. Pathological examination removed a piece of skin tissue, 16 × 12 × 0.3cm, the surface is black, no bulge. The section shows that the dark area is 0.1 cm deep. See also a pile of red-brown tissue, the size of 4 × 3 × 1cm, which found nine lymph node-like tissue, ranging from 0.2cm to 0.5cm in diameter. The basal surface of the epidermis can be seen as nests, cords, or diffusely distributed nevus cell clusters. Nesting nevus cell clusters can be seen in the direct skin. Lymph nodes can be seen in the cutaneous sinus, lymphoid follicles or nests or stripes between the follicles