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目的了解消化性溃疡胃镜检出率,并对疾病相关因素及其并发症、癌前病变进行分析。方法对2002～2007年在我院经胃镜检查确诊为消化性溃疡患者的病史及胃镜资料结果进行回顾性分析。结果(1)本组资料消化性溃疡患者中幽门螺杆菌(Hp)阳性率为56.41%,阴性率为41.82%。Hp阳性者以41～50岁年龄组最多见,少见于20岁以下和80岁以上年龄组。(2)我科5年来消化性溃疡患者中并发出血112例(2.26%),梗阻62例(1.25%),癌变108例(2.18%),未发现穿孔患者。(3)消化性溃疡患者中取胃黏膜活检751例,占15.51%,其中腺体萎缩23例,上皮内瘤变136例,肠上皮化生35例,上皮内瘤变并肠上皮化生20例。结论消化性溃疡是多发常见病,消化性溃疡Hp感染率较高(56.4%),应重视消化性溃疡常见并发症,常规镜下活检与病理诊断相结合有助于提高早期癌变诊断率。
Objective To understand the detection rate of peptic ulcer gastroscopy and to analyze the related factors of the disease and its complications and precancerous lesions. Methods A retrospective analysis was conducted on the history of patients with peptic ulcer diagnosed by gastroscopy in our hospital from 2002 to 2007 and the data of gastroscopy. Results (1) The positive rate of Helicobacter pylori (Hp) in this group of patients with peptic ulcer was 56.41%, the negative rate was 41.82%. Hp positive in the 41 to 50 age group the most common, rare in 20 years of age and 80 years of age or older. (2) There were 112 cases (2.26%) of patients with peptic ulcer concurrently in our department in 5 years, 62 cases (1.25%) of obstruction and 108 cases (2.18%) of canceration. No perforation was found. (3) Gastric mucosal biopsy in patients with peptic ulcer 751 cases, accounting for 15.51%, of which 23 cases of glandular atrophy, 136 cases of intraepithelial neoplasia, 35 cases of intestinal metaplasia, intraepithelial neoplasia and intestinal metaplasia 20 example. Conclusions Peptic ulcer is a common disease with high incidence of peptic ulcer infection (56.4%). Common complications of peptic ulcer should be emphasized. The combination of routine microscopic biopsy and pathological diagnosis can help improve the diagnosis rate of early canceration.