脑损伤后普遍存在的炎性反应激活补体并通过多种途径导致和加重继发性脑损伤。膜攻击复合物具有直接破坏血脑屏障、促使红细胞溶解、促进释放细胞因子、氧自由基和金属基质蛋白、加剧炎症反应的生物特性,从而加重继发性脑损伤。本文对膜攻击复合物造成继发性脑损伤的研究进行综述,希望能对相关研究和法医学鉴定提供参考。 Inflammatory reactions that are prevalent after brain injury activate complement and lead and exacerbate secondary brain damage through a variety of pathways. Membrane attack complex can directly damage the blood-brain barrier, promote erythrocyte lysis, promote the release of cytokines, oxygen free radicals and metal matrix proteins, aggravate the biological characteristics of inflammatory reactions, thereby aggravating secondary brain injury. This review summarizes the research on secondary brain injury caused by membrane attack complex, and hopes to provide references for related research and forensic identification.