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目的探讨子宫动脉栓塞联合甲氨蝶呤治疗子宫切口瘢痕妊娠的临床疗效。方法选取96例子宫切口瘢痕妊娠患者,随机分为实验组和对照组,分别给予子宫动脉栓塞联合甲氨蝶呤治疗和单纯甲氨蝶呤治疗,比较两组患者临床疗效、阴道出血量、术中出血量、阴道出血量、月经出血时间、病灶消失时间、β-HCG恢复时间及住院时间,并分析不良反应。结果实验组患者治愈率显著高于对照组,患者阴道出血量和术中出血量较对照组患者显著降低,阴道出血时间、月经出血时间、病灶消失时间、β-HCG恢复时间及住院时间较对照组患者均显著缩短,差异均有统计学意义(P<0.05),不良反应发生率比较差异未见统计学意义(P>0.05)。结论子宫动脉栓塞联合甲氨蝶呤治疗子宫切口瘢痕妊娠可显著提高治愈率,加快患者的恢复时间,缩短住院时间,且安全、可靠,值得进一步在临床上推广。
Objective To investigate the clinical efficacy of uterine artery embolization combined with methotrexate in the treatment of uterine incision scar pregnancy. Methods 96 cases of uterine incision scar pregnancy were randomly divided into experimental group and control group, respectively, given uterine artery embolization combined methotrexate and methotrexate treatment, the clinical efficacy of two groups were compared, vaginal bleeding, surgery The amount of bleeding, vaginal bleeding, menstrual bleeding time, the disappearance of lesions, β-HCG recovery time and hospital stay, and analysis of adverse reactions. Results The cure rate of experimental group was significantly higher than that of control group. The volume of vaginal bleeding and intraoperative blood loss in patients in experimental group were significantly lower than those in control group. Vaginal bleeding time, menstrual bleeding time, disappearance of lesions, recovery time of β-HCG and hospital stay were significantly The patients in the two groups were significantly shortened, the differences were statistically significant (P <0.05), the incidence of adverse reactions was no significant difference (P> 0.05). Conclusion Uterine artery embolization combined with methotrexate in the treatment of uterine incision scar pregnancy can significantly improve the cure rate, speed up the recovery time of patients, shorten the hospital stay, and safe, reliable and worth further promotion in the clinic.