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Objective:use Meridian dredging abdominal manipulation to treat simple obesity,observes to the changes of fat metabolism.Methods:60 cases were treated by Meridian dredging abdominal manipulation.Through its own comparison before and after treatment to observes the changes of Lipid index and evaluate the effects of massage.Results:The lipid index changes obviously around the massage.Therapeutic effect of the treatment group was significantly better than the control group( P <0.05).The disparation of two groups lipid、leptin and leptin receptor levels before and after the treatment have statistically significant ( P < 0.05).Conclusions:Meridian dredging abdominal manipulation can significantly reduce the lipid and leptin content,and improve the content of leptin receptors,and can promote the fat metabolism.