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目的探索射频消融术(RFA)在肝细胞肝癌(简称肝癌)根治性治疗中的临床应用价值。方法检索近年来有关RFA在肝癌治疗中应用的文献并进行综述。结果肝脏移植、肝切除术和RFA是目前被认为具有治愈性治疗效果的3种方法,其中RFA由于具有较好的局部肿瘤控制效果,近年来较多地用于肝脏移植术前的减瘤治疗,在延长患者的等待期的同时不增加病例脱落及死亡的危险。虽然RFA与肝脏切除术对小肝癌的疗效目前尚有争论,但是RFA联合肝脏切除术,扩大了肝癌患者的手术指征,提高了疗效。结论由于RFA技术良好的局部肿瘤控制能力和微创特点,使其在肝癌的各种治疗策略中发挥越来越重要的作用,并与肝移植及肝部分切除术的优点相互补充,使更多的肝癌患者受益。无论是哪一种治疗方法,术中最大程度地减少残癌的发生率,术后密切随访,复发后积极地治疗才是提高疗效的根本。
Objective To explore the clinical value of radiofrequency ablation (RFA) in radical treatment of hepatocellular carcinoma (HCC). Methods To search and review the literature about the application of RFA in the treatment of liver cancer in recent years. Results Liver transplantation, hepatectomy and RFA are the three methods currently considered to be curative curative effect. Among them, RFA has been widely used in the treatment of cytoreductive liver transplantation in recent years because of its good local tumor control effect , In extending the patient’s waiting period without increasing the risk of case shedding and death. Although RFA and liver resection on the efficacy of small liver cancer is still controversial, but RFA combined with hepatectomy, liver cancer patients to expand the surgical indications and improve the efficacy. Conclusion Due to the good local tumor control and minimally invasive features of RFA technique, it plays an increasingly important role in various treatment strategies for hepatocellular carcinoma and complements the advantages of liver transplantation and partial hepatectomy so that more Of liver cancer patients benefit. No matter what kind of treatment, surgery to minimize the incidence of residual cancer, follow-up after surgery, active treatment after recurrence is to improve the efficacy of the fundamental.