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EB病毒(EBV)是一类疱疹病毒,在人类引起传染性单核细胞增多症(下称传单),而且和非洲的Burkitt′s淋巴瘤、鼻咽癌、较少的低丙种球蛋白血症有密切关系。EBV引起的传单的几个特征包括高丙球蛋白血症及出现明显的非典型淋巴细胞的淋巴细胞增多症。这种淋巴细胞增多症主要是T细胞增多的结果。在人类病因中只有EBV最易感染B细胞。最近的研究证明,将EBV加入人淋巴细胞培养可引起B细胞多克隆的激活,成为分泌IgG、IgA和IgM的淋巴细胞。我们研究了十二例急性EBV诱发的传单患者的B细胞激活和免疫调节细胞的功
Epstein-Barr virus (EBV) is a group of herpes viruses that cause infectious mononucleosis (hereinafter referred to as leaflets) in humans and is associated with Burkitt’s lymphoma, nasopharyngeal cancer, less hypoalbuminemia in Africa There is a close relationship. Several features of EBV-induced leaflets include hypergammaglobulinemia and lymphocytosis with pronounced atypical lymphocytes. This lymphocytosis is mainly the result of increased T cells. Only EBV is most susceptible to B cells in human disease. Recent studies have shown that the addition of EBV to human lymphocyte culture can cause the polyclonal activation of B cells to become lymphocytes that secrete IgG, IgA and IgM. We studied the effects of B-cell activation and immunoregulatory cell function in twelve patients with acute EBV-induced leaflets