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合成并表征了手性配体SalenH2 及其锰配合物 .详细讨论了配体及配合物的红外光谱、电子吸收光谱和圆二色光谱性质 .研究结果表明 ,SalenMn(III)配合物在水溶液中为Δ构型 ,进一步证明了配合物中双偶氮螯环结构的确具有很高的刚性 .用紫外 -可见光谱滴定方法测定了锰配合物与氨基酸分子识别过程的缔合常数 ,实验结果表明 :主体SalenMn(III)对每一对氨基酸对映异构体的识别能力均表现为对D 型的识别能力比对L 型大 ,对具有相同对映构型的不同氨基酸客体的识别能力按Phe ,Val和Thr顺序依次递减 .圆二色光谱 (CD)考察结果与热力学研究结果一致 .此外 ,采用分子力学方法考察了主客体体系的最低能量构象 ,并对该构象进行了量子化学计算 ,从理论上对实验事实作了进一步解释 .
The complexes of SalenH2 and its complexes were synthesized and characterized.The IR spectra, electron absorption spectra and circular dichroism spectra of the ligands and complexes were discussed in detail.The results show that SalenMn (III) complexes in aqueous solution For the Δ configuration, further confirmed that the structure of the double-azole chela ring is indeed very high rigidity.Using UV-Vis spectrophotometry to determine the association constant between the manganese complex and the amino acid molecule recognition process, the experimental results show that: The recognition ability of the main SalenMn (III) for each pair of amino acid enantiomers showed that the recognition ability to D type is larger than that to L type, and the recognition ability to different amino acid guests with the same enantiomeric configuration is in the order of Phe, Val and Thr.According to the results of circular dichroism spectroscopy (CD), the results are consistent with the results of thermodynamics.Moreover, the lowest energy conformation of the host-guest system is investigated by molecular mechanics method, and the quantum chemical calculation of the conformation is carried out.From the theory On the experimental facts made further explanation.