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目的 :探索孕妇生殖道支原体感染与低出生体重儿的病因学关系。方法 :经产前检查支原体阳性孕妇 488例 ,按实验分组方法随机分成红霉素干预组和非干预组 ,比较两组间孕妇支原体感染阴转率、母婴传播率和低出生体重儿的发生率。结果 :红霉素干预组解脲脲原体 (Ureaplasma urealyticum ,Uu)的阴转率和母婴传播率低于非干预组 ,差异有显著性 (P<0 .0 5 ) ,而人型支原体 (Mycoplasm a hominis,Mh)的阴转率及母婴传播率在组间无显著性差异 (P>0 .0 5 )。干预组中低出生体重儿的发生率显著低于非干预组 (P<0 .0 5 )。结论 :红霉素干预措施能有效地降低孕妇解脲脲原体感染 ,阻断其母婴传播 ,降低低出生体重儿发生率
Objective: To explore the relationship between mycoplasma infection in pregnant women and etiology of low birth weight infants. Methods: 488 pregnant women with mycoplasma were tested prenatally and randomly divided into erythromycin intervention group and non-intervention group according to experimental grouping method. The incidence of mycoplasma infection negative conversion, maternal-infant transmission and low birth weight were compared between the two groups rate. Results: The negative conversion rate and mother-to-infant transmission rate of Ureaplasma urealyticum (Uu) in erythromycin intervention group were significantly lower than those in non-intervention group (P <0.05), while the Mycoplasma hominis (Mycoplasma a hominis, Mh) negative rate and mother-to-child transmission rate between the two groups showed no significant difference (P> 0.05). The incidence of low birth weight infants in intervention group was significantly lower than that in non-intervention group (P <0.05). Conclusion: Erythromycin intervention can effectively reduce the infection of Ureaplasma urealyticum in pregnant women, block the transmission of maternal and infant, and reduce the incidence of low birth weight infants