川崎氏病,又称皮肤粘膜淋巴结综合征,是病因不明的急性发热性疾病,主要累及全身血管特别是冠状动脉。造成冠状动脉瘤,是川崎病患儿死亡的主要病因。川崎病存在多样的血液学异常,其改变同心脏损害有较明显的关系。现将有关进展综述如下。川崎病和血小板的关系川崎病的尸解证实血小板参与了动脉内血栓的形成过程。血小板增多本身是非特异性的表现,在伴有或不伴有血管炎的炎性疾病,血小板计数增加是一个常见的实验检查发现。因此,川崎病血小板计数增加是全身性炎症的一种表现,而血小板计数增高对冠状动脉损害无预测作用。继发于冠状动脉瘤的心肌梗塞是川崎病儿死亡的主要原因,故冠状动脉瘤的形成同血小板的关 Kawasaki disease, also known as mucocutaneous lymph node syndrome, is an unknown cause of acute febrile illness, mainly involving the systemic blood vessels, especially the coronary arteries. Coronary artery aneurysm, is the leading cause of death in children with Kawasaki disease. Kawasaki disease there is a variety of hematological abnormalities, the change has a more obvious relationship with cardiac damage. The relevant progress is summarized below. Kawasaki disease and platelet Kawasaki disease autopsy confirmed that platelets involved in the formation of intra-arterial thrombosis. Thrombocytosis itself is a nonspecific manifestation. In inflammatory diseases with or without vasculitis, an increase in platelet count is a common laboratory test found. Therefore, Kawasaki disease increased platelet count is a manifestation of systemic inflammation, and increased platelet count no predictive effect on coronary artery lesions. Myocardial infarction secondary to coronary aneurysm is the leading cause of death in children with Kawasaki disease, so the formation of coronary aneurysms with the platelets off