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Purpose:To investigate the effects of hormone administration upon epithelium healing in patients with recurrent corneal epithelial exfoliation. Methods:The recurrence rate of 56 patients with recurrent corneal epithelial exfoliation was compared after 3-month follow up,30 patients of whom received the basic treatment of bFGF and pressure bandage plus prednisone administration (combination treatment group, ie. A) and the other 26 patients received the basic treatment alone (single treatment group, ie. B). Results:No patients showed recurrence in the combination treatment group. But there were 20 patients (76.92%) in the basic treatment group recurred.χ2 test showed that χ2=35.9. The two groups had significant difference regarding the recurrence of corneal epithelial exfoliation(P<0.01). Conclusion:For the patients with recurrent corneal epithelial exfoliation,hormone administration should be considered to reduce the recurrence and protect the function of cornea as a supplement to the basic treatment.
Purpose: To investigate the effects of hormone administration upon epithelium healing in patients with recurrent corneal epithelial exfoliation. Methods: The recurrence rate of 56 patients with recurrent corneal epithelial exfoliation was compared after 3-month follow up, 30 patients of whom received the basic treatment of bFGF and pressure bandage plus prednisone administration (combination treatment group, ie. A) and the other 26 patients received the basic treatment alone (single treatment group, ie. B). Results: No patients showed recurrence in the combination treatment group. But The two groups had significant difference regarding the recurrence of corneal epithelial exfoliation (P <0.01). Conclusion: For the patients with recurrent corneal epithelial exfoliation, hormone administration should be considered to reduce the recurrence and protect the function of cornea as a supplement to the basic treatment.