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在大鼠脑突触体上，０．０１～１００μｍｏｌ／Ｌ的Ｎ受体激动剂烟碱可浓度依赖性地增加对同浓度４５Ｃａ２＋（１．０μｍｏｌ／Ｌ）的摄取量，并为１．０μｍｏｌ／ＬＮ受体拮抗剂美加明所对抗。相同条件下，１．０μｍｏｌ／Ｌ烟碱也可显著增加脑突触体对不同浓度４５Ｃａ２＋（０．１～１００μｍｏｌ／Ｌ）的摄取量。提示烟碱作用于脑Ｎ受体，可增加脑突触体对钙离子的摄取量
In rat brain synaptosomes, 0.01 ~ 100μmol / L N-receptor agonist nicotine increased the uptake of 45Ca2 + (1.0μmol / L) in a concentration-dependent manner and was 1.0μmol / LN receptor antagonist mecamylamine confrontation. Under the same conditions, 1.0μmol / L nicotine also significantly increased the uptake of 45Ca2 + (0.1 ~ 100μmol / L) in brain synaptosomes. Tip nicotine on the brain N receptor, can increase the brain synaptosomes uptake of calcium